O'Keefe M, Mulvihill A, Yeoh P L
Eye Department, The Childrens Hospital, Dublin, Ireland.
J Cataract Refract Surg. 2000 Dec;26(12):1758-64. doi: 10.1016/s0886-3350(00)00561-7.
To determine the safety and efficacy of bilateral intraocular lens (IOL) implantation in children.
Tertiary referral pediatric ophthalmology department.
This retrospective study comprised 13 children (26 eyes) who had bilateral cataract surgery with IOL implantation. Patients were divided into 2 groups: congenital cases, diagnosed during the first year of life, and developmental cases, diagnosed after 1 year of age. All patients had small incision phacoemulsification with primary implantation of a poly(methyl methacrylate) or a foldable acrylic IOL. Primary posterior capsulotomy was performed in 16 eyes (61.5%).
Age at surgery ranged from 1 week to just under 8 years. Seven patients (53.8%) had a systemic diagnosis: Down's syndrome (n = 4); developmental delay or cerebral atrophy (n = 3). Five children with systemic problems could not cooperate with formal vision testing; 2 could fix and follow bilaterally, and 3 had central, steady, and maintained vision bilaterally. In the congenital group, 37.5% of eyes attained a visual acuity of 20/20 and 87.5%, 20/120 or better. In the developmental group, formal vision testing was possible in 4 children. Five eyes (83.3%) attained a visual acuity of 20/40 or better. Thirteen eyes (50.0%) required posterior capsulotomy. Primary posterior capsulotomy reduced the incidence of posterior capsule opacification (PCO), but there was no correlation between PCO and IOL material. One patient developed glaucoma bilaterally.
Bilateral IOL implantation was safe and produced good visual results in children of all ages with bilateral cataract.
确定儿童双眼人工晶状体(IOL)植入术的安全性和有效性。
三级转诊儿科眼科。
这项回顾性研究包括13例接受双眼白内障手术并植入IOL的儿童(26只眼)。患者分为两组:先天性病例,在出生后第一年内确诊;发育性病例,在1岁以后确诊。所有患者均接受小切口超声乳化术,并一期植入聚甲基丙烯酸甲酯或可折叠丙烯酸IOL。16只眼(61.5%)进行了一期后囊切开术。
手术年龄从1周至近8岁。7例患者(53.8%)有全身性诊断:唐氏综合征(4例);发育迟缓或脑萎缩(3例)。5例有全身性问题的儿童无法配合正规视力检查;2例双眼能注视和追视,3例双眼有中心、稳定和持续的视力。在先天性组中,37.5%的眼视力达到20/20,87.5%的眼视力达到20/120或更好。在发育性组中,4例儿童可以进行正规视力检查。5只眼(83.3%)视力达到20/40或更好。13只眼(50.0%)需要进行后囊切开术。一期后囊切开术降低了后囊混浊(PCO)的发生率,但PCO与IOL材料之间无相关性。1例患者双眼发生青光眼。
双眼IOL植入术对所有年龄的双眼白内障儿童均安全且能产生良好的视觉效果。