用于鉴定金黄色葡萄球菌的乳胶凝集试验的国际多中心评估
International multicenter evaluation of latex agglutination tests for identification of Staphylococcus aureus.
作者信息
van Griethuysen A, Bes M, Etienne J, Zbinden R, Kluytmans J
机构信息
Department of Clinical Microbiology, St. Elisabeth Hospital, Tilburg, The Netherlands.
出版信息
J Clin Microbiol. 2001 Jan;39(1):86-9. doi: 10.1128/JCM.39.1.86-89.2001.
A newly marketed rapid agglutination kit for the identification of Staphylococcus aureus, Slidex Staph Plus (bioMérieux), was compared to Staphaurex Plus (Murex Diagnostics) and Pastorex Staph-Plus (Sanofi Diagnostics Pasteur). The study took place in three clinical microbiology laboratories in three different European countries. A total of 892 staphylococcal isolates, including 278 methicillin-sensitive S. aureus (MSSA) isolates, 171 methicillin-resistant S. aureus (MRSA) isolates, and 443 coagulase-negative staphylococcal isolates, were analyzed. The sensitivities (MSSA/MRSA) and specificities, respectively, were 98. 2% (98.9%/97.1%) and 98.9% for Slidex Staph Plus, 98.2% (98.2%/98. 2%) and 96.2% for Staphaurex Plus, and 98.7% (98.6%/98.8%) and 95.7% for Pastorex Staph Plus. The specificity of the Slidex Staph Plus kit was statistically significantly higher than the specificities of Staphaurex Plus and Pastorex Staph-Plus. The Slidex Staph Plus is a very reliable test for the identification of S. aureus.
一种新上市的用于鉴定金黄色葡萄球菌的快速凝集试剂盒——Slidex Staph Plus（生物梅里埃公司），与Staphaurex Plus（Murex诊断公司）和Pastorex Staph-Plus（赛诺菲巴斯德诊断公司）进行了比较。该研究在欧洲三个不同国家的三个临床微生物实验室开展。共分析了892株葡萄球菌分离株，其中包括278株甲氧西林敏感金黄色葡萄球菌（MSSA）分离株、171株甲氧西林耐药金黄色葡萄球菌（MRSA）分离株和443株凝固酶阴性葡萄球菌分离株。Slidex Staph Plus的敏感性（MSSA/MRSA）和特异性分别为98.2%（98.9%/97.1%）和98.9%，Staphaurex Plus为98.2%（98.2%/98.2%）和96.2%，Pastorex Staph Plus为98.7%（98.6%/98.8%）和95.7%。Slidex Staph Plus试剂盒的特异性在统计学上显著高于Staphaurex Plus和Pastorex Staph-Plus的特异性。Slidex Staph Plus是一种用于鉴定金黄色葡萄球菌的非常可靠的检测方法。
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