亚得里亚海中部（卡斯特拉湾）近岸水域中7-表-栉齿状毒素-2 海人草酸的出现情况。

The occurrence of 7-epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kastela Bay).

作者信息

Pavela-Vrancic M, Mestrović V, Marasović I, Gillman M, Furey A, James K K

机构信息

Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of Split, N. Tesle 12, 21000 Split, Croatia.

出版信息

Toxicon. 2001 Jun;39(6):771-9. doi: 10.1016/s0041-0101(00)00203-8.

DOI:10.1016/s0041-0101(00)00203-8

PMID:11137535

Abstract

Okadaic acid (OA) and 7-epi-pectenotoxin-2 seco acid (7-epi-PTX-2SA) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shellfish toxicity has been associated with the occurrence of the Dinophysis species. This is the first report on the incidence of 7-epi-PTX-2SA in the Adriatic region.

摘要

冈田酸（OA）和7-表-pectenotoxin-2 去甲酸（7-表-PTX-2SA）被确定为亚得里亚海中部贻贝中的毒性决定因素。通过与来自爱尔兰的尖锐鳍藻藻提取物中存在的毒素进行色谱比较以及质谱分析，证实了pectenotoxin-2衍生物的性质。贝类毒性的来源与鳍藻属物种的出现有关。这是关于亚得里亚海地区7-表-PTX-2SA发生率的首次报告。