Petrofsky J S, Laymon M
Department of Physical Therapy, Loma Linda University, CA 92350, USA.
Eur J Appl Physiol. 2000 Nov;83(4 -5):274-82. doi: 10.1007/s004210000294.
A group of 45 male subjects were examined in a cross-sectional study to compare the blood pressure response that occurs during isometric exercise maintained to fatigue among control subjects and paraplegic patients with (PH) and without essential hypertension (PN). Two muscle groups were examined: the handgrip muscles (voluntary effort) and the quadriceps muscles. The tension chosen for the contraction was 40% of the muscles maximum strength for both muscle groups. While the paraplegic groups had more strength in their handgrip muscles than that found for the controls, the control subjects had more strength in their quadriceps muscles than either of the paraplegic groups. During the fatiguing isometric contractions, the rate of rise and absolute systolic blood pressure was higher in the PH than the other groups of subjects. The diastolic pressure of the PH group, while elevated during exercise, was only elevated to the same degree as the increase in resting diastolic pressure above normal. Heart rate changes during exercise was the same in all groups of subjects for handgrip contractions. The controls had the same heart rate response to handgrip as to leg exercise. The paraplegic groups showed no heart rate change during fatiguing contractions of their quadriceps muscles. The PH group actually showed a reduction in heart rate during the leg exercise.
在一项横断面研究中，对45名男性受试者进行了检查，以比较对照组、患有（PH）和未患有原发性高血压（PN）的截瘫患者在持续进行等长运动直至疲劳期间的血压反应。检查了两组肌肉：握力肌（自主用力）和股四头肌。两组肌肉收缩时所选用的张力均为肌肉最大力量的40%。虽然截瘫组握力肌的力量比对照组更大，但对照组股四头肌的力量比任何一组截瘫患者都更大。在疲劳性等长收缩期间，PH组受试者收缩压的上升速率和绝对值高于其他组。PH组的舒张压虽然在运动期间升高，但仅升高到与静息舒张压高于正常水平时的升高程度相同。在进行握力收缩时，所有组受试者运动期间的心率变化相同。对照组对握力的心率反应与腿部运动时相同。在股四头肌进行疲劳性收缩期间，截瘫组未出现心率变化。在腿部运动期间，PH组实际上出现了心率下降。
