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[施氏葡萄球菌引起的起搏器感染]

[Pacemaker infection caused by Staphylococcus schleiferi].

作者信息

Mitsutake K, Ura T, Sawai T, Katayama Y, Miyatake K

出版信息

Kansenshogaku Zasshi. 2000 Nov;74(11):980-3. doi: 10.11150/kansenshogakuzasshi1970.74.980.

Abstract

Pacemaker infection is one of the severe complication of pacemaker implantation. We report a case of pacemaker infection caused by Staphylococcus schleiferi which is a coagulase-negative staphylococcus, and its relation with human infection is not well characterized. In 1994, a 80-year-old male presented with a pacemaker pocket infection, cutaneous inflammation but no fever 2 months after insertion of a pacemaker. S. schleiferi was isolated from the pus. The patient was given cefazolin for 5 days. One month later he was readmitted because of cutaneous inflammation and the extruded generator was removed. S. schleiferi was isolated from the generator. After the patient was treated with cefazolin for 3 weeks, four consecutive wound cultures were all negative. A new generator was inserted on the same side. One month after re-insertion, the patient again presented a cutaneous inflammation, and S. schleiferi was isolated from the pus as well as the generator and the leads on their removal. Twenty-six days later, a new pacing system was inserted on the other side. There was no further recurrence of the infection. Removal of the entire pacing system was necessary to cure the infection. We expect further information of human infections caused by S. schleiferi.

摘要

起搏器感染是起搏器植入的严重并发症之一。我们报告一例由施氏葡萄球菌引起的起搏器感染病例,施氏葡萄球菌是一种凝固酶阴性葡萄球菌,其与人类感染的关系尚未完全明确。1994年,一名80岁男性在植入起搏器2个月后出现起搏器囊袋感染、皮肤炎症,但无发热。从脓液中分离出施氏葡萄球菌。患者接受头孢唑林治疗5天。1个月后,他因皮肤炎症再次入院,取出了外露的发生器。从发生器中分离出施氏葡萄球菌。患者接受头孢唑林治疗3周后,连续4次伤口培养均为阴性。在同一侧植入了一个新的发生器。重新植入1个月后,患者再次出现皮肤炎症,取出脓液、发生器和导线时均分离出施氏葡萄球菌。26天后,在另一侧植入了一个新的起搏系统。感染未再复发。必须移除整个起搏系统才能治愈感染。我们期待获得更多关于施氏葡萄球菌引起人类感染的信息。

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