Levin C, Maibach H I
Department of Dermatology, University of California at San Francisco Medical Center, 94143-0989, USA.
Contact Dermatitis. 2000 Dec;43(6):317-21. doi: 10.1034/j.1600-0536.2000.043006317.x.
We review controlled trials of corticosteroid effect in experimentally elicited acute nickel contact dermatitis in man, in the hope of clarifying optimal efficacy for clinical use. To maximize discrimination and objectivity, we focus on data with 1 well-characterized allergen, nickel, in studies utilizing bioengineering documentation. Higher potency corticosteroids are effective (unlike in experimental irritant contact dermatitis), but optimum schedules still require definition.
我们回顾了关于皮质类固醇对人体实验性诱发的急性镍接触性皮炎影响的对照试验，以期阐明其临床使用的最佳疗效。为了最大限度地提高区分度和客观性，我们聚焦于使用生物工程记录的研究中，关于一种特征明确的变应原——镍的数据。高效能皮质类固醇是有效的（与实验性刺激性接触性皮炎不同），但最佳用药方案仍有待确定。
