Leong S P, Wong J H
Department of Surgery, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94115, USA.
Surg Clin North Am. 2000 Dec;80(6):1839-44. doi: 10.1016/s0039-6109(05)70266-8.
Selective sentinel lymphadenectomy is a standard staging procedure for patients with melanoma and is rapidly evolving into a standard procedure for breast cancer. A well-trained, multidisciplinary team is essential for the success of such a procedure. Clinical trials are under way to determine the clinical significance of sentinel lymph nodes in melanoma and breast cancer. The techniques of harvesting are being developed in other solid cancers, such as gynecologic and gastrointestinal cancer. Cellular and molecular techniques are being used to study the mechanism of micrometastasis.
选择性前哨淋巴结切除术是黑色素瘤患者的标准分期手术，并且正迅速发展成为乳腺癌的标准手术。一个训练有素的多学科团队对于此类手术的成功至关重要。目前正在进行临床试验以确定前哨淋巴结在黑色素瘤和乳腺癌中的临床意义。在其他实体癌，如妇科癌和胃肠道癌中，正在开发获取前哨淋巴结的技术。正在使用细胞和分子技术来研究微转移的机制。
