吩噻嗪类药物与心电图
Phenothiazines and the electrocardiogram.
作者信息
Jeeva Raj M V, Benson R
出版信息
Postgrad Med J. 1975 Feb;51(592):65-8. doi: 10.1136/pgmj.51.592.65.
Abstract
Fifty-nine (42%) of 140 schizophrenic patients taking phenothiazines were found to have abnormal electrocardiograms. The abnormalities included T wave changes, S-T depression, P-R and Q-T prolongation, persistent sinus tachycardia (110 or more/min) and right bundle branch block. In forty-eight (34%) of the fifty-nine patients, the ECG abnormalities disappeared after stopping the phenothiazine and reappeared on its resumption.
摘要
在140名服用吩噻嗪类药物的精神分裂症患者中，有59名（42%）被发现心电图异常。这些异常包括T波改变、S-T段压低、P-R和Q-T间期延长、持续性窦性心动过速（每分钟110次或以上）以及右束支传导阻滞。在这59名患者中的48名（34%）中，停用吩噻嗪类药物后心电图异常消失，恢复用药时又再次出现。
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1
2
Cardiac changes related to phenothiazine therapy, with special reference to thioridazine.
J Am Geriatr Soc. 1967 Jan;15(1):20-8. doi: 10.1111/j.1532-5415.1967.tb05330.x.
3
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JAMA. 1966 Oct 3;198(1):134-8. doi: 10.1001/jama.198.1.134.
4
Cardiovascular complications in young patients taking psychotropic drugs. A preliminary report.服用精神药物的年轻患者的心血管并发症。初步报告。
Am Heart J. 1969 Dec;78(6):757-69. doi: 10.1016/0002-8703(69)90442-6.
5
Intramyocardial lesions in patients dying suddenly and unexpectedly.猝死和意外死亡患者的心肌内病变
JAMA. 1966 Jan 24;195(4):254-60.
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