Boddy K, Glaros D, Robertson I
Phys Med Biol. 1975 Jan;20(1):80-7. doi: 10.1088/0031-9155/20/1/007.
Factors influencing the precision of measuring changes in the calcium content of sections of bone, including vertebrae, using reactor neutrons for partial body in vivo activation analysis have been examined and quantified. These factors include (a) the choice of incidient neutron spectrum, (b) the uniformity of activation with depth in the body, (c) reproducibility, (d) interfering reactions, (e) sensitivity and (f) dosimetry. It is concluded that an overall precision of 2.8%-3.2% (coefficient of variation) can be attained with a neutron dose of 50 mrad or 3-4% with a dose as low as 20 mrad.
对使用反应堆中子进行全身活体活化分析来测量包括椎骨在内的骨切片钙含量变化的精度的影响因素进行了研究和量化。这些因素包括:(a) 入射中子能谱的选择;(b) 体内深度方向活化的均匀性;(c) 可重复性;(d) 干扰反应;(e) 灵敏度;(f) 剂量测定。得出的结论是,中子剂量为50毫拉德时可实现2.8%-3.2%(变异系数)的总体精度,剂量低至20毫拉德时精度为3%-4%。