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[会厌炎——一种儿科疾病?]

[Epiglottitis--a pediatric disease?].

作者信息

Schüpbach J, Bachmann D, Hotz M A

机构信息

Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten, Hals-, Kiefer- und Gesichtschirurgie, Inselspital Bern.

出版信息

Schweiz Med Wochenschr. 2000;Suppl 125:35S-37S.

Abstract

Epiglottitis, commonly described as a paediatric disease, also occurs in adults. Early diagnosis and immediate treatment are crucial because of the rapid and possibly lethal course of upper airway obstruction due to swelling. Initial treatment consists in securing the upper airway and in antibiotic treatment. Streptococci and, especially in children, Haemophilus influenzae b are the most common bacteria. Our study focused on clinical and epidemiological changes since children started to be vaccinated against Haemophilus influenzae b in Switzerland (1992). We reviewed patient histories of 31 adults and 88 children who were hospitalised with epiglottitis at the University Hospital of Berne between 1989 and 1999. Our findings show that the incidence of epiglottitis in children, a clinically, epidemiologically and bacteriologically homogeneous disease, has dramatically decreased. Epiglottitis in adults presents as a more heterogeneous disease without change since the beginning of the vaccination programme. Due to the variety of germs it is impossible to recommend vaccination for adults against Haemophilus influenzae b.

摘要

会厌炎通常被认为是一种儿科疾病,但也会发生在成人身上。由于肿胀导致上呼吸道梗阻发展迅速且可能致命,因此早期诊断和及时治疗至关重要。初始治疗包括确保上呼吸道通畅和进行抗生素治疗。链球菌,尤其是在儿童中,b型流感嗜血杆菌是最常见的细菌。我们的研究聚焦于自瑞士(1992年)开始对儿童接种b型流感嗜血杆菌疫苗以来的临床和流行病学变化。我们回顾了1989年至1999年间在伯尔尼大学医院因会厌炎住院的31名成人和88名儿童的病历。我们的研究结果表明,会厌炎在儿童中是一种临床、流行病学和细菌学上均一的疾病,其发病率已大幅下降。自疫苗接种计划开始以来,成人会厌炎表现为一种更为异质性的疾病,发病率没有变化。由于病菌种类繁多,不建议对成人接种b型流感嗜血杆菌疫苗。

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