Gerber M, Flückiger U, Wolfensberger M
HNO-Universitätsklinik Basel.
Schweiz Med Wochenschr. 2000;Suppl 125:7S-10S.
Although extensive studies on the use of antibiotics during and after surgery exist, antibiotics are still used too liberally.
To analyse the appropriateness of antibiotic use in ENT surgery.
Retrospective study of all surgical procedures performed at the Department of Otolaryngology, Head and Neck Surgery of the University of Basel between April and June 1999. Of the 174 procedures 30 were classified clean, 50 clean-contaminated (group A), 69 clean-contaminated (group B), 14 contaminated, and 11 dirty.
9% of all patients received inappropriate antibiotic prophylaxis and 4% inappropriate primary antibiotic treatment. 22% of antibiotic prophylaxis, 39% of primary antibiotic treatments and 29% of secondary antibiotic treatments were considered inappropriate.
The too liberal use of antibiotics during and after surgery is largely due to the surgeon's fear of infectious complications. Only a peer-review process of all antibiotic prescriptions can reduce the inappropriate use of antibiotics.
尽管针对手术期间及术后使用抗生素已有广泛研究，但抗生素的使用仍过于随意。
分析耳鼻喉科手术中抗生素使用的合理性。
对巴塞尔大学头颈外科耳鼻喉科1999年4月至6月间进行的所有外科手术进行回顾性研究。在174例手术中，30例为清洁手术，50例为清洁-污染手术（A组），69例为清洁-污染手术（B组），14例为污染手术，11例为污秽手术。
所有患者中有9%接受了不适当的抗生素预防，4%接受了不适当的初始抗生素治疗。22%的抗生素预防、39%的初始抗生素治疗以及29%的二次抗生素治疗被认为是不适当的。
手术期间及术后抗生素使用过于随意很大程度上是由于外科医生担心感染并发症。只有对抗生素处方进行同行评审程序才能减少抗生素的不适当使用。
