Rowińska-Marcińska K, Szmidt-Sałkowska E, Kopeć A, Wawro A, Karwańska A
Department of Neurology, Medical University of Warsaw, 1a Banach St., 02-097 Warsaw, Poland.
Electromyogr Clin Neurophysiol. 2000 Oct-Nov;40(7):431-9.
The aim of present study was to analyse the motor unit (MU) changes in progressive muscle dystrophy (PMD) and in inflammatory myopathy (IM) and to evaluate eventual neurogenic factors in MU reorganisation. The material consisted of 20 patients with (PMD), 20 patients with (IM) and 20 healthy age-matched volunteers. The shape of concentric needle motor unit potentials (cn MUPs), including their duration, amplitude, area, size index and number of phases, the interference pattern and the amplitude and area of macro MUPs were evaluated. The cn emg data satisfied the classical criteria for myopathy in all examined patients, at least in one of the tested muscles. A decreased amplitude and/or area of macro MUPs, compatible with myopathy, were observed in 32 of the 40 patients. In some cases of chronic IM and PDM the long duration polyphasic potentials were recorded. The size index (SI) value of long polyphasic MUPs was usually decreased or normal. This feature indicated that desynchronisation of "myopathic" MUPs results from a reduced number of muscle fibers and their degeneration and regeneration. The results indicated no difference in MU reorganization between PMD and IM and no evidence of neurogenic factors in MU changes.
本研究的目的是分析进行性肌肉营养不良（PMD）和炎性肌病（IM）中运动单位（MU）的变化，并评估MU重组中可能存在的神经源性因素。研究材料包括20例PMD患者、20例IM患者和20名年龄匹配的健康志愿者。评估了同心针电极运动单位电位（cn MUPs）的形态，包括其时限、波幅、面积、大小指数和相数，干扰型以及宏MUPs的波幅和面积。在所有受检患者中，至少在一块受检肌肉中，cn肌电图数据符合肌病的经典标准。40例患者中有32例观察到与肌病相符的宏MUPs波幅和/或面积降低。在一些慢性IM和PDM病例中记录到了时限长的多相电位。长多相MUPs的大小指数（SI）值通常降低或正常。这一特征表明，“肌病性”MUPs的去同步化是由于肌纤维数量减少及其变性和再生所致。结果表明，PMD和IM之间在MU重组方面没有差异，且没有证据表明MU变化中存在神经源性因素。
