Ida K, Kamiya T
Dept. of Surgery, Kosai General Hospital.
Gan To Kagaku Ryoho. 2000 Dec;27(14):2263-6.
A 62-year-old woman suffering from gallbladder stone had a remarkably high preoperative CEA level of 525 ng/ml. Computed tomography revealed swollen mediastinal lymph nodes. Lymph node biopsy during thoracotomy led to a diagnosis of metastasis from poorly differentiated adenocarcinoma. Although thorough examinations were performed, the origin of the adenocarcinoma could not be detected. In this case, induced hypertensive chemotherapy with angiotensin II was effective. The mediastinal lymph nodes diminished remarkably and the patient's CEA level decreased to 22 ng/ml. Induced hypertensive chemotherapy with angiotensin II might be a useful treatment for cancer metastases of unknown origin.
一名62岁患有胆囊结石的女性患者术前癌胚抗原（CEA）水平显著升高，达525 ng/ml。计算机断层扫描显示纵隔淋巴结肿大。开胸手术期间进行的淋巴结活检诊断为低分化腺癌转移。尽管进行了全面检查，但未检测到腺癌的原发部位。在该病例中，使用血管紧张素II进行诱导性高血压化疗有效。纵隔淋巴结明显缩小，患者的CEA水平降至22 ng/ml。使用血管紧张素II进行诱导性高血压化疗可能是治疗不明原发部位癌症转移的一种有效方法。
