Vysotskiĭ V V
Zh Mikrobiol Epidemiol Immunobiol. 1979 Jun(6):58-61.
A population of Corynebacterium diphtheriae may consist of cells with accented (osmiophilic) cytoplasm (cells of the "dark" type, or D type) and cells with cytoplasm having no pronounced osmiophilic properties (cells of the "clear" type, or C type). The divergence of the population into cells of the D and C types occurs at the stage of cell division, the original mother cell being able to divide into 2 or more individual cells belonging to different types (elongated multiseptate cells). At the same time no morphological disturbances in septation may be observed. The ability of each type of cells for division into the corresponding individual daughter cells indicates their being biologically valid. The mixed (D--C) population of Corynebacterium diphtheriae is considered to be a sign of the dissociation of bacterial culture.
白喉棒状杆菌群体可能由细胞质浓密(嗜锇性)的细胞(“深色”型细胞,即D型细胞)和细胞质无明显嗜锇性的细胞(“浅色”型细胞,即C型细胞)组成。群体分化为D型和C型细胞发生在细胞分裂阶段,原始母细胞能够分裂成2个或更多属于不同类型的单个细胞(细长的多隔细胞)。同时,在分隔过程中未观察到形态学干扰。每种类型的细胞分裂成相应单个子细胞的能力表明它们具有生物学活性。白喉棒状杆菌的混合(D - C)群体被认为是细菌培养物解离的标志。