Orrett F A
University of the West Indies, Department of Pathology and Microbiology, Eric Williams Medical Sciences Complex, Champs Fleurs, Mount Hope, Trinidad and Tobag, West Indies.
Ethiop Med J. 2000 Apr;38(2):85-91.
Between July 2-3, 1998, six infants on the neonatal intensive care unit (ICU) at San Fernando General Hospital died following septicemia with multi-resistant Pseudomonas aeruginosa. All patients were infected with the same strain and all were resistant to gentamicin, tobramycin, piperacillin and ceftazidime. Samples of hand washing liquids from the hands of the neonatal ICU staff were cultured and no P. aeruginosa was detected. Patients' environment and environmental surfaces: latches and interiors of incubators, sink traps and the operating theater environment and suction tubing were cultured, and P. aeruginosa with the same antibiogram was recovered from the suction tubing and the sink trap of the only tap on the neonatal ICU. Following the intervention of the infection control team and their strong re-emphasis on compliance with proper hand washing procedures and sterilization techniques, no cluster of infection with this strain or any other strain of P. aeruginosa were subsequently observed. The infecting strain may have been transferred from the operating theater via a neonate delivered by caesarean section and from this infant to the others by a neonatal health care worker who failed to wash hands properly between patients. This is the first documented fatal P. aeruginosa outbreak described at the San Fernando General hospital.
1998年7月2日至3日期间，圣费尔南多综合医院新生儿重症监护病房（ICU）的6名婴儿在感染多重耐药铜绿假单胞菌败血症后死亡。所有患者均感染了同一菌株，且均对庆大霉素、妥布霉素、哌拉西林和头孢他啶耐药。对新生儿ICU工作人员手上的洗手液样本进行培养，未检测到铜绿假单胞菌。对患者的环境和环境表面进行培养，包括培养箱的门闩和内部、水槽存水弯、手术室环境以及吸引管，从新生儿ICU唯一水龙头的吸引管和水槽存水弯中分离出具有相同抗菌谱的铜绿假单胞菌。在感染控制团队进行干预并大力再次强调遵守正确的洗手程序和消毒技术后，随后未观察到该菌株或任何其他铜绿假单胞菌菌株的感染聚集情况。感染菌株可能是通过剖宫产分娩的新生儿从手术室传播而来，并由一名新生儿医护人员在患者之间未正确洗手，从而从该婴儿传播给其他婴儿。这是圣费尔南多综合医院记录的首例致命铜绿假单胞菌暴发事件。
