Hypertension and unilateral hydronephrosis.

Three patients with unilateral hydronephrosis, a normal contralateral kidney, and sustained hypertension were investigated by means of arteriography and differential renal vein renin determinations. The close correlation of the onset of hypertension to the obstructive uropathy, as well as the increased renin production from the affected side, were indicative of a causal relationship. Nephrectomy produced a prompt cure of hypertension in each instance.