Hicsönmez G, Dalat E, Erbengi G
Acta Haematol. 1979;61(5):283-7. doi: 10.1159/000207673.
Reticuloendothelial phagocytic capacity (REPC) was determined in 14 children with beta-thalassemia major, by means of technetium 99m sulfur colloid uptake, who had not had splenectomy. No difference was observed in the REPC between patient and controls. The REPC of liver and spleen were evaluated separately by determining the half-time for the clearance of 99mTc from the blood. The REPC of both liver and spleen in patients was expected to be decreased when compared with controls; however, we found that the REPC of the liver was increased in patients and that there was no difference between patients' and controls' spleen values. This suggests that chronic anemia and hemosiderosis do not alter the REPC in beta-thalassemia major.
通过锝99m硫胶体摄取法，对14例未行脾切除术的重型β地中海贫血患儿的网状内皮系统吞噬能力（REPC）进行了测定。患者与对照组之间的REPC未观察到差异。通过测定血液中99mTc清除的半衰期，分别评估肝脏和脾脏的REPC。与对照组相比，预计患者肝脏和脾脏的REPC均会降低；然而，我们发现患者肝脏的REPC增加，且患者与对照组的脾脏值无差异。这表明慢性贫血和含铁血黄素沉着症不会改变重型β地中海贫血的REPC。
