Caldicott D G, Kuhn M
Emergency Department, Royal Adelaide Hospital, Adelaide, SA, Australia.
Ann Emerg Med. 2001 Jan;37(1):99-102. doi: 10.1067/mem.2001.111642.
Gamma-hydroxybutyrate was introduced as an anesthetic agent in the 1960s and is still used in some countries, despite recognized disadvantages. More recently, it has emerged as a popular recreational drug. We report 3 cases of gamma-hydroxybutyrate overdose, the effects of which were reversed by the administration of low-dose intravenous physostigmine. The origins of this regimen and the case for physostigmine as a potential antidote are described.
γ-羟基丁酸在20世纪60年代被作为一种麻醉剂引入，尽管存在公认的缺点，但仍在一些国家使用。最近，它已成为一种流行的消遣性毒品。我们报告了3例γ-羟基丁酸过量中毒病例，通过静脉注射低剂量毒扁豆碱可逆转其影响。本文描述了该治疗方案的起源以及毒扁豆碱作为潜在解毒剂的情况。
