Hudson M E
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.
Semin Cell Dev Biol. 2000 Dec;11(6):475-83. doi: 10.1006/scdb.2000.0204.
The application of Arabidopsis genetics to research into the responses of plants to light has enabled rapid recent advances in this field. The plant photoreceptor phytochrome mediates well-defined responses that can be exploited to provide elegant and specific genetic screens. By this means, not only have mutants affecting the phytochromes themselves been isolated, but also mutants affecting the transduction of phytochrome signals. The genes involved in these processes have now begun to be characterized by using this genetic approach to isolate signal transduction components. Most of the components characterized so far are capable of being translocated to the cell nucleus, and they may help to define a new system of regulation of gene expression. This review summarises the ongoing contribution made by genetics to our understanding of light perception and signal transduction by the phytochrome system.
拟南芥遗传学在植物对光反应研究中的应用，使得该领域近期取得了快速进展。植物光感受器光敏色素介导明确的反应，可用于开展精妙且特异的遗传筛选。通过这种方式，不仅分离出了影响光敏色素自身的突变体，还分离出了影响光敏色素信号转导的突变体。目前，利用这种遗传方法分离信号转导组分，参与这些过程的基因已开始得到表征。到目前为止，所表征的大多数组分都能够转运到细胞核中，它们可能有助于定义一种新的基因表达调控系统。本综述总结了遗传学在我们理解光敏色素系统的光感知和信号转导方面所做的持续贡献。
