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Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-jewish caucasian sample.

作者信息

Dettling M, Cascorbi I, Roots I, Mueller-Oerlinghausen B

出版信息

Arch Gen Psychiatry. 2001 Jan;58(1):93-4. doi: 10.1001/archpsyc.58.1.93.

DOI:10.1001/archpsyc.58.1.93
PMID:11146763
Abstract
摘要

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HLA-B38 and clozapine-induced agranulocytosis in Israeli Jewish schizophrenic patients.以色列犹太精神分裂症患者中HLA - B38与氯氮平所致粒细胞缺乏症
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Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens.氯氮平诱导的白种人精神分裂症患者粒细胞缺乏症:证实与人类白细胞Ⅰ类和Ⅱ类抗原关联的线索
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HLA associations in clozapine-induced agranulocytosis.
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Human leukocyte antigen typing, response to neuroleptics, and clozapine-induced agranulocytosis in jewish Israeli schizophrenic patients.以色列犹太裔精神分裂症患者的人类白细胞抗原分型、对抗精神病药物的反应及氯氮平所致粒细胞缺乏症
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Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis.确定氯氮平所致粒细胞缺乏症有效药物遗传学检测的特征。
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