Tokish J T, Benjamin J, Walter F
Sections of Orthopedic Surgery, The University of Arizona Health Sciences Center, Tucson, USA.
J Orthop Trauma. 2001 Jan;15(1):5-9. doi: 10.1097/00005131-200101000-00002.
To review a regional experience with the treatment of snakebites.
Five major southern Arizona hospitals, including two Level I trauma centers.
A review of all snakebite admissions over a five-year period was performed.
During the period reviewed, 164 patients were admitted for snakebites. Rattlesnakes were responsible for 98 percent of identified envenomations. Thirty-six percent of the patients were transported by air to the admitting facility. Eighty percent of patients were admitted to the intensive care unit for an average of 1.6 days. Total hospital stays averaged 2.8 days. Ninety percent of patients received antivenin, usually only on the day of admission. Of those receiving antivenin, 20 percent had an anaphylactoid reaction, and 1 percent required readmission for serum sickness. Laboratory evaluation indicated abnormalities in platelet count, coagulation parameters, and fibrinogen levels, but these rarely required treatment. Thirteen percent of patients underwent surgical intervention, including a 4 percent fasciotomy rate, and a single amputation.
The use of field treatment, including "cut and suck," tourniquets, and cryotherapy, increased the likelihood of surgery. The authors concluded that the intensive care unit and helicopter transport system were overused. They recommend that established objective envenomation severity scores be used to dictate patient treatment, specifically the use of antivenin.
回顾蛇咬伤治疗的区域经验。
亚利桑那州南部的五家主要医院,包括两家一级创伤中心。
对五年期间所有蛇咬伤入院病例进行回顾。
在回顾期间,164例患者因蛇咬伤入院。响尾蛇导致了98%已确认的中毒事件。36%的患者通过空运被送往收治机构。80%的患者被收入重症监护病房,平均住院1.6天。总住院时间平均为2.8天。90%的患者接受了抗蛇毒血清治疗,通常仅在入院当天。在接受抗蛇毒血清治疗的患者中,20%发生类过敏反应,1%因血清病需要再次入院。实验室检查显示血小板计数、凝血参数和纤维蛋白原水平异常,但这些情况很少需要治疗。13%的患者接受了手术干预,包括4%的筋膜切开率和1例截肢。
现场治疗方法,包括“切开吸出法”、止血带和冷冻疗法,增加了手术的可能性。作者得出结论,重症监护病房和直升机转运系统被过度使用。他们建议使用既定的客观中毒严重程度评分来指导患者治疗,特别是抗蛇毒血清的使用。