Wicks A C, Clain D J
Am J Dig Dis. 1975 Jan;20(1):1-8. doi: 10.1007/BF01073130.
Steatorrhea due to chronic pancreatitis was found in 23 percent of a consecutive series of 107 new african diabetics; 3 had pancreatic calcification. Of 16, 14 had definitely abnormal exocirne secretion function testing using secreation pancreozymin stimultion. Themorphology and function of the small intestine were normal by local standards. When compared with diabetics without steatorrhea they weighed less, their fasting blood sugars were lower, and their insulin requirements were greater. High alcoholic intake might be significant cause, but the incidence was similar in the diabetics without steatorrhea. No evidence of childhood or adult malnutrition was established. The etiology of this high incidence of chronic pancreatitis among african diabetics remains unexplained.
在连续收治的107例新诊断的非洲糖尿病患者中,23%发现有慢性胰腺炎所致的脂肪泻;3例有胰腺钙化。16例中,14例使用促胰液素刺激试验进行外分泌功能检测,结果肯定异常。按当地标准,小肠的形态和功能正常。与无脂肪泻的糖尿病患者相比,他们体重较轻,空腹血糖较低,但胰岛素需求量较大。高酒精摄入量可能是一个重要原因,但在无脂肪泻的糖尿病患者中发病率相似。未发现儿童期或成人期营养不良的证据。非洲糖尿病患者中慢性胰腺炎高发的病因仍无法解释。