Hultgren H N, Swenson R, Wettach G
Am J Med. 1975 Jan;58(1):139-42. doi: 10.1016/0002-9343(75)90545-8.
Cardiac arrest developed in two patients after the administration of oral potassium. Neither patient had renal insufficiency, but both had underlying heart disease. In one patient fatal ventricular fibrillation developed 4 days after he received an aortic valve replacement for aortic stenosis and while he was receiving oral potassium supplements. The serum potassium level before cardiac arrest was 8.1 meq. The second patient had angina and was given 40 meq of potassium orally 15 minutes after an exercise test which produced chest pain and S-T segment depression. One hour later, ventricular fibrillation developed. Resuscitation was successful. Both patients had electrocardiographic evidence of hyperkalemia. Oral administration of potassium may produce severe cardiac toxicity in patients with heart disease even when renal function is clinically normal.
两名患者在口服钾后发生心脏骤停。两名患者均无肾功能不全，但都有基础心脏病。一名患者在接受主动脉瓣置换术治疗主动脉狭窄后4天，在服用口服钾补充剂时发生致命性室颤。心脏骤停前血清钾水平为8.1毫当量。第二名患者患有心绞痛，在运动试验诱发胸痛和ST段压低后15分钟口服40毫当量钾。1小时后发生室颤。复苏成功。两名患者均有高钾血症的心电图证据。即使肾功能临床正常，口服钾在心脏病患者中也可能产生严重的心脏毒性。
