Holtås S, Geijer B, Strömblad L G, Maly-Sundgren P, Burtscher I M
Department of Radiology, University Hospital, 22185 Lund, Sweden.
Neuroradiology. 2000 Nov;42(11):824-7. doi: 10.1007/s002340000431.
Diffusion-weighted imaging (DWI) has been reported to be useful in the differential diagnosis between abscesses and cystic or necrotic tumours. However, experience is still limited and the true sensitivity and specificity remain to be determined. Our purpose is to describe a ring-enhancing metastasis of adenocarcinoma with a DWI pattern similar to that reported for abscesses. The tumour had a diameter of 1.5 cm and give signal from its centre similar to that of normal brain on T1-weighted images, whereas it was increased on T2-weighted images, and surrounded by a low signal ring, suggesting a capsule. The signal was high on DWI and the apparent diffusion coefficient (ADC) was low (0.55 x 10(-3) mm2/s). The findings were misinterpreted as representing an abscess in the early capsule-formation stage, but the signal pattern probably represented early tumour necrosis with intracellular oedema, but without liquefaction. Findings on DWI during the early capsule formation stage in abscesses and early tumour necrosis are probably similar and must be interpreted with caution.
据报道,扩散加权成像(DWI)在脓肿与囊性或坏死性肿瘤的鉴别诊断中很有用。然而,经验仍然有限,真正的敏感性和特异性仍有待确定。我们的目的是描述一例腺癌环形强化转移灶,其DWI表现与报道的脓肿相似。该肿瘤直径为1.5 cm,在T1加权图像上其中心信号与正常脑相似,而在T2加权图像上信号增强,并被低信号环包围,提示有包膜。DWI上信号高,表观扩散系数(ADC)低(0.55×10⁻³ mm²/s)。这些表现最初被误诊为处于早期包膜形成阶段的脓肿,但这种信号模式可能代表早期肿瘤坏死伴细胞内水肿,但无液化。脓肿早期包膜形成阶段和早期肿瘤坏死的DWI表现可能相似,必须谨慎解读。