节杆菌属对角鲨烯的氧化降解作用
Oxidative degradation of squalene by Arthrobacter species.
作者信息
Yamada Y, Motoi H, Kinoshita S, Takada N, Okada H
出版信息
Appl Microbiol. 1975 Mar;29(3):400-4. doi: 10.1128/am.29.3.400-404.1975.
Abstract
An organism isolated from soil and identified as Arthrobacter sp. was studied for its squalene degradation. The degradation product from squalene, which accumulated in the culture broth, was isolated and identified as trans-geranylacetone by mass spectrometry, gas chromatography, infrared spectrometry, and nuclear magnetic resonance spectrometry. Addition of a high concentration of K2HPO4 to the culture medium resulted in accumulation of fairly large amounts of carboxylic acids in addition to geranylacetone. These carboxylic acids were identified as isovaleric, beta,beta'-dimethylacrylic, geranic, and (plus)-(R)-citronellic acids. Among these acids, alpha,beta-saturated carboxylic acids were found to be predominant in quantity.
摘要
从土壤中分离出并鉴定为节杆菌属的一种微生物，对其角鲨烯降解情况进行了研究。在培养液中积累的角鲨烯降解产物，通过质谱、气相色谱、红外光谱和核磁共振光谱进行分离和鉴定，确定为反式香叶基丙酮。向培养基中添加高浓度的磷酸氢二钾，除了香叶基丙酮外，还导致大量羧酸的积累。这些羧酸被鉴定为异戊酸、β,β'-二甲基丙烯酸、香叶酸和(+)-(R)-香茅酸。在这些酸中，α,β-饱和羧酸在数量上占主导地位。
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