Lidén C, Johnsson S
Occupational and Environmental Dermatology, Department of Medicine, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
Contact Dermatitis. 2001 Jan;44(1):7-12. doi: 10.1034/j.1600-0536.2001.440102.x.
Nickel allergy is by far the most frequent contact allergy, affecting 10-15% of women in the general population, and causing dermatitis and hand eczema. The EU Nickel Directive, aimed at the prevention of nickel allergy, comes fully into force by July 2001. The Directive covers piercing materials, items in contact with the skin, and requirements on resistance to wear. We carried out a study of the prevalence on the market, before the Nickel Directive, of items that release nickel and of nickel in piercing posts. Nickel release, as shown by a positive dimethylglyoxime (DMG) test, was detected in 25% of 725 items intended for direct and prolonged contact with the skin. Of 15 posts intended for use during epithelialization after piercing, 60% contained more than 0.05% nickel. These products do not comply with the requirements of the EU Nickel Directive. It is suggested that experts in contact dermatitis participate in the prevention of nickel allergy by explaining its effects: the r le of skin exposure and which parts of an item are in contact with the skin, and the crucial question of nickel release versus nickel content.
镍过敏是目前最常见的接触性过敏,影响着普通人群中10%至15%的女性,会引发皮炎和手部湿疹。旨在预防镍过敏的欧盟镍指令于2001年7月全面生效。该指令涵盖穿孔材料、与皮肤接触的物品以及耐磨性要求。我们对镍指令实施前市场上释放镍的物品以及穿孔柱中的镍进行了患病率研究。通过阳性丁二酮肟(DMG)测试表明,在725件旨在与皮肤直接和长期接触的物品中,25%检测出镍释放。在15根用于穿孔后上皮化过程的柱子中,60%所含镍超过0.05%。这些产品不符合欧盟镍指令的要求。建议接触性皮炎专家通过解释镍过敏的影响来参与预防工作:皮肤接触的作用、物品的哪些部分与皮肤接触,以及镍释放与镍含量的关键问题。