Tsuyuguchi N, Matsuoka Y, Sunada I, Matsusaka Y, Haque M
Department of Neurosurgery, Osaka City University Medical School, Osaka, Japan.
AJNR Am J Neuroradiol. 2001 Feb;22(2):311-3.
We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA.
我们报告了一例患有颞叶癫痫的多形性黄色星形细胞瘤(PXA)患者。影像学检查序列包括磁共振成像(MR),正电子发射断层扫描(PET)使用[18F] - 氟脱氧葡萄糖(FDG)和[11C] - 蛋氨酸(Met)示踪剂的结果显示,有一个代谢活跃区域等同于或几乎等同于正常脑皮质,提示该肿瘤可能具有恶性潜能。组织病理学检查结果显示为低级别胶质瘤。PXA葡萄糖代谢活跃的机制尚不清楚;然而,FDG - PET获得的阳性结果可能并不总是表明与PXA相关的恶性程度。