The "memory" of salivary gland cells.

In experiments on dogs with a chronic fistual of the submandibular salivary gland intravenous or subcutaneous injection of pilocarpine at intervals of a few days was accompanied by a gradual increase in the volume of saliva, reaching a maximum after 5 injections. Retention of the 'trace' of the action of pilocarpine was observed also in experiments on a dog with vago-sympathetic anastomosis and subsequent parasympathetic denervation of the gland.