Hosokawa M, Mihich E, Watanabe T, Pressman D
Cancer Res. 1975 Mar;35(3):591-5.
Growth of Sarvoma 180 in AKR mice was enhanced by immunization with frozen-thawed homogenates of this tumor. Treatment of host mice with rabbit antimyeloma cell antiserum, either furing immunization or shortly after tumor implantation, resulted in a decreased incidence of tumor rejection or an increased rate of tumor growth. A slow-growing subline from a spontaneous, DBA/2Ha-DD mammary tumor is rejected after initial growth in DBA/2J mice. The incidence of rejection was reduced by treatment with the antiserum studied.
用该肿瘤的冻融匀浆对AKR小鼠进行免疫可增强肉瘤180的生长。在免疫期间或肿瘤植入后不久，用兔抗骨髓瘤细胞抗血清处理宿主小鼠，会导致肿瘤排斥发生率降低或肿瘤生长速率增加。来自自发的DBA/2Ha-DD乳腺肿瘤的一个生长缓慢的亚系在DBA/2J小鼠中初始生长后会被排斥。所研究的抗血清处理可降低排斥发生率。
