Siddiqui M M, Shuaib A
Stroke Research Unit, Walter Mackenzie Health Sciences Center, Edmonton, Alberta, Canada.
Methods. 2001 Jan;23(1):83-94. doi: 10.1006/meth.2000.1108.
In vivo intracerebral microdialysis is an important neurochemical technique that has been used extensively in the experimental setting. Relatively recently, techniques have been developed to utilize this method in human subjects. The past decade has seen the advent of clinical investigations utilizing in vivo microdialysis in a number of neuropathological states. This review summarizes the principles of in vivo microdialysis techniques, as applied to humans, while discussing the significance of recent investigations for future clinical development.
体内脑微透析是一项重要的神经化学技术，已在实验环境中广泛应用。相对较近的时候，已开发出在人类受试者中使用该方法的技术。在过去十年中，出现了在多种神经病理状态下利用体内微透析进行的临床研究。本综述总结了应用于人类的体内微透析技术的原理，同时讨论了近期研究对未来临床发展的意义。
