Ziegler R, Minne H, Raue F, Paar G, Delling G
Dtsch Med Wochenschr. 1975 Feb 28;100(9):415-6, 419-23. doi: 10.1055/s-0028-1106230.
In three women intoxication with vitamin D or dihydrotachysterol occurred. Two patients died from complications despite successful lowering of the serum calcium, the third died after a pulmonary embolus during hypercalcaemia 5 months after cessation of vitamin D. Correct observation of the narrow therapeutic range of vitamin D preparations appears most important in the treatment of hypoparathyroidism and other indications. Particular attention should be given to the prophylaxis of over dosage. Apart from regular serum calcium estimations instruction of the patient and relatives as to the dangers and symptoms of intoxication is recommended. The issuing of a therapy identity card would meet these requirements.
有三名女性发生了维生素D或二氢速甾醇中毒。尽管成功降低了血清钙水平，但仍有两名患者死于并发症，第三名患者在停用维生素D 5个月后高钙血症期间发生肺栓塞后死亡。在甲状旁腺功能减退症和其他适应症的治疗中，正确观察维生素D制剂狭窄的治疗范围似乎最为重要。应特别注意预防用药过量。除了定期测定血清钙外，建议告知患者及其亲属中毒的危险和症状。发放治疗身份卡将满足这些要求。
