Zargar A H, Masoodi S R, Khan A K, Bashir M I, Laway B A, Wani A I, Dar F A
Department of Endocrinology, Sheri-Kashmir Institute of Medical Sciences Srinagar, Post Box 1098, GPO 190001, J&K, Srinagar, India.
Diabetes Res Clin Pract. 2001 Feb;51(2):145-9. doi: 10.1016/s0168-8227(00)00232-1.
This study was carried out to determine the relationship between impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) in a North Indian population. The data in 5083 subjects studied earlier was reanalyzed by applying new WHO diagnostic criteria. Reanalysis revealed that 305 (6.0%) subjects had diabetes mellitus (198 on the basis of fasting plasma glucose of > or =7.0 mmol/l (> or =126 mg/dl) and an additional 107 based on a 2-h glucose tolerance test), 381 (7.5%) had IFG and 361 (7.1%) had IGT. Of these 361 subjects with IGT, only 99 (27.4%) had impaired fasting glucose whereas 262 (72.6%) had normal fasting glucose of <6.1 mmol/l (<110 mg/dl). Of 381 subjects with IFG, 99 (26%) had IGT where as 282 (74%) had normal 2-hr glucose. We conclude that there is a poor correlation between IGT and IFG.
本研究旨在确定印度北部人群中空腹血糖受损(IFG)与糖耐量受损(IGT)之间的关系。通过应用世界卫生组织新的诊断标准,对早前研究的5083名受试者的数据进行了重新分析。重新分析显示,305名(6.0%)受试者患有糖尿病(198名基于空腹血糖≥7.0 mmol/l(≥126 mg/dl),另有107名基于2小时葡萄糖耐量试验),381名(7.5%)患有IFG,361名(7.1%)患有IGT。在这361名IGT受试者中,只有99名(27.4%)空腹血糖受损,而262名(72.6%)空腹血糖正常,<6.1 mmol/l(<110 mg/dl)。在381名IFG受试者中,99名(26%)患有IGT,而282名(74%)2小时血糖正常。我们得出结论,IGT与IFG之间的相关性较差。