Schlegel A, Lisanti M P
Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA.
J Cell Physiol. 2001 Mar;186(3):329-37. doi: 10.1002/1097-4652(2001)9999:9999<000::AID-JCP1045>3.0.CO;2-0.
Caveolins are a family of proteins that coat the cytoplasmic face of caveolae, vesicular invaginations of the plasma membrane. These proteins are central to the organization of the proteins and lipids that reside in caveolae. Caveolins transport cholestrol to and from caveolae, and they regulate the activity of signaling proteins that reside in caveolae. Studying the genes encoding the caveolae coat proteins, we have learned much about how they perform these multiple functions.
小窝蛋白是一类蛋白质家族，它们覆盖在小窝（质膜的囊泡状内陷结构）的胞质面。这些蛋白质对于小窝中存在的蛋白质和脂质的组织至关重要。小窝蛋白在小窝内外运输胆固醇，并调节存在于小窝中的信号蛋白的活性。通过研究编码小窝包被蛋白的基因，我们对它们如何执行这些多种功能有了很多了解。
