利用FimCH复合物进行疫苗接种作为预防大肠杆菌尿路感染的一种策略。 - Suppr

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Vaccination utilizing the FimCH complex as a strategy to prevent Escherichia coli urinary tract infections.

作者信息

Langermann S, Ballou W R

机构信息

MedImmune, Inc., 35 W. Watkins Mill Rd., Gaithersburg, MD 20878, USA.

出版信息

J Infect Dis. 2001 Mar 1;183 Suppl 1:S84-6. doi: 10.1086/318857.

DOI:10.1086/318857

PMID:11171023

Abstract

摘要

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Vaccination utilizing the FimCH complex as a strategy to prevent Escherichia coli urinary tract infections.

作者信息

Langermann S, Ballou W R

机构信息

MedImmune, Inc., 35 W. Watkins Mill Rd., Gaithersburg, MD 20878, USA.

出版信息

J Infect Dis. 2001 Mar 1;183 Suppl 1:S84-6. doi: 10.1086/318857.

DOI:10.1086/318857

PMID:11171023

Abstract

摘要

相似文献

Vaccination utilizing the FimCH complex as a strategy to prevent Escherichia coli urinary tract infections.

J Infect Dis. 2001 Mar 1;183 Suppl 1:S84-6. doi: 10.1086/318857.

Vaccination with FimH adhesin protects cynomolgus monkeys from colonization and infection by uropathogenic Escherichia coli.

J Infect Dis. 2000 Feb;181(2):774-8. doi: 10.1086/315258.

Systemic immunization with conserved pilus-associated adhesins protects against mucosal infections.

Dev Biol Stand. 1998;92:117-22.

New vaccines may ward off urinary tract infections.

Science. 1997 Apr 25;276(5312):533. doi: 10.1126/science.276.5312.533.

Structure and function of Escherichia coli type 1 pili: new insight into the pathogenesis of urinary tract infections.

J Infect Dis. 2001 Mar 1;183 Suppl 1:S36-40. doi: 10.1086/318855.

Immune response against adhesins of enteroaggregative Escherichia coli immunized by three different vaccination strategies (DNA/DNA, Protein/Protein, and DNA/Protein) in mice.

Comp Immunol Microbiol Infect Dis. 2010 May;33(3):215-25. doi: 10.1016/j.cimid.2008.10.002. Epub 2008 Dec 3.

[New findings on alpha-hemolytic strains of E. coli in urinary tract infections. I. alpha-hemolysin and adhesins].

Cesk Epidemiol Mikrobiol Imunol. 1992 Jun;41(2):78-81.

Microbiology. Pods invade infected bladders.

Science. 2003 Jul 4;301(5629):31. doi: 10.1126/science.301.5629.31a.

[Candidate vaccine against urinary tract infections].

Ned Tijdschr Geneeskd. 2001 Sep 22;145(38):1860-2.

Vaccination with recombinant FimH fused with flagellin enhances cellular and humoral immunity against urinary tract infection in mice.

Vaccine. 2013 Feb 6;31(8):1210-6. doi: 10.1016/j.vaccine.2012.12.059. Epub 2013 Jan 7.

引用本文的文献

Engineering and Evaluation of a Live-Attenuated Vaccine Candidate with Enhanced Type 1 Fimbriae Expression to Optimize Protection Against Typhimurium.

Vaccines (Basel). 2025 Jun 19;13(6):659. doi: 10.3390/vaccines13060659.

Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.

PLoS Pathog. 2025 Feb 19;21(2):e1012325. doi: 10.1371/journal.ppat.1012325. eCollection 2025 Feb.

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference.

bioRxiv. 2024 Dec 14:2024.12.06.627246. doi: 10.1101/2024.12.06.627246.

Vaccination with a combination of planktonic and biofilm virulence factors confers protection against carbapenem-resistant Acinetobacter baumannii strains.

Sci Rep. 2022 Nov 19;12(1):19909. doi: 10.1038/s41598-022-24163-z.

Immunomodulation therapy offers new molecular strategies to treat UTI.

Nat Rev Urol. 2022 Jul;19(7):419-437. doi: 10.1038/s41585-022-00602-4. Epub 2022 Jun 22.

Loss of an Intimin-Like Protein Encoded on a Uropathogenic E. coli Pathogenicity Island Reduces Inflammation and Affects Interactions with the Urothelium.

Infect Immun. 2022 Feb 17;90(2):e0027521. doi: 10.1128/IAI.00275-21. Epub 2021 Dec 6.

Local induction of bladder Th1 responses to combat urinary tract infections.

Proc Natl Acad Sci U S A. 2021 Mar 9;118(10). doi: 10.1073/pnas.2026461118.

Dimeric and Trimeric Fusion Proteins Generated with Fimbrial Adhesins of Uropathogenic .

Front Cell Infect Microbiol. 2016 Oct 31;6:135. doi: 10.3389/fcimb.2016.00135. eCollection 2016.

Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.

Cell Host Microbe. 2016 Oct 12;20(4):482-492. doi: 10.1016/j.chom.2016.08.013. Epub 2016 Sep 22.

A high-throughput assay for the measurement of uropathogenic Escherichia coli attachment to urinary bladder cells.

Int J Exp Pathol. 2016 Apr;97(2):194-201. doi: 10.1111/iep.12181. Epub 2016 Jun 8.