Karnam Umaprasanna S., Rosen Charles M., Raskin Jeffrey B.
Division of Gastroenterology, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140, USA.
Curr Treat Options Gastroenterol. 2001 Feb;4(1):15-21. doi: 10.1007/s11938-001-0043-1.
Treatment of small intestinal ulcers depends on the cause of the ulcers. Ulcerations of the small intestine (apart from duodenal ulcers) are uncommon. Two diverse syndromes of idiopathic small bowel ulcerations include the isolated nonspecific ulcer and idiopathic chronic ulcerative enteritis (ICUE). Treatment of isolated nonspecific ulcers include discontinuation of medications known to cause nonspecific ulcerations, balloon dilation of strictures, and segmental resection of involved segments. Treatment of ICUE includes a diet trial of gluten restriction and consideration of early surgery because of the potential for associated malignancies. Steroid therapy has not been shown to be effective in the treatment of ICUE.
小肠溃疡的治疗取决于溃疡的病因。小肠溃疡(十二指肠溃疡除外)并不常见。特发性小肠溃疡的两种不同综合征包括孤立性非特异性溃疡和特发性慢性溃疡性肠炎(ICUE)。孤立性非特异性溃疡的治疗包括停用已知会导致非特异性溃疡的药物、对狭窄进行球囊扩张以及对受累节段进行节段性切除。ICUE的治疗包括进行无麸质饮食试验,并考虑早期手术,因为可能存在相关恶性肿瘤。尚未证明类固醇疗法对ICUE的治疗有效。