Mole D R, Tomson C R, Mortensen N, Winearls C G
Oxford Kidney Unit, The Churchill, Oxford Radcliffe Hospitals, Oxford, UK.
QJM. 2001 Feb;94(2):69-77. doi: 10.1093/qjmed/94.2.69.
Jejuno-ileal bypass has until recently been an accepted treatment for refractory morbid obesity. Although hyperoxaluria causing renal tract calculi is a well-recognized complication, we describe eight patients who developed significant renal failure attributable to hyperoxaluria resulting from this procedure, three requiring renal replacement therapy. We review the literature, describing 18 other cases with renal failure, the mechanisms of hyperoxaluria and its treatment. Because reversal of the bypass may result in stabilization or partial improvement of renal function, these patients require long-term follow-up of renal function.
直到最近，空肠回肠旁路术仍是治疗难治性病态肥胖的一种公认疗法。尽管高草酸尿症导致尿路结石是一种广为人知的并发症，但我们描述了8例因该手术导致高草酸尿症而出现严重肾衰竭的患者，其中3例需要肾脏替代治疗。我们回顾了文献，描述了另外18例肾衰竭病例、高草酸尿症的发病机制及其治疗方法。由于逆转旁路术可能会使肾功能稳定或部分改善，这些患者需要对肾功能进行长期随访。
