Trägårdh G, Lynch P R, Vinciguerra T
Radiology. 1975 Apr;115(1):59-62. doi: 10.1148/115.1.59.
Metrizamide is a new non-ionic radiopaque agent with low osmolarity and low intravenous toxicity. Hyperosmolarity is one of the factors involved in the decrease of myocardial contracility, alterations of aortic pressure, and disturbances in the cardiac rhythm which contrast media induce during coronary angiography. Metrizamide has been compared to other commonly used contrast media and was shown to produce fewer changes on the cardiac functions recorded.
甲泛葡胺是一种新型的非离子型不透X线造影剂，具有低渗透压和低静脉毒性。高渗透压是冠状动脉造影期间造影剂引起心肌收缩力下降、主动脉压力改变和心律紊乱的因素之一。已将甲泛葡胺与其他常用造影剂进行了比较，结果表明它对所记录的心脏功能产生的变化较少。
