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[人脑肿瘤来源的6种细胞系中糖脂与肿瘤发生相关性的研究]

[Study of a correlation between glycolipids and tumorigenesis in 6 cell lines derived from human brain tumors].

作者信息

Maunoury R, Morelec M J, Hauttecoeur B, Ensergueix D, Vedrenne C

出版信息

C R Seances Acad Sci D. 1979 Mar 5;288(9):851-4.

PMID:111871
Abstract

By silica gel chromatography we have studied the various glycolipids of six established lines derived from human brain tumors. Among the glycolipids, the GM3 ganglioside appeared as one of the major components in the three lines rejected by athymic nude Mice. On the contrary, GM3 was absent, or present in trace, in the three tumorigenic lines.

摘要

通过硅胶色谱法,我们研究了源自人脑肿瘤的六个已建立细胞系中的各种糖脂。在这些糖脂中,GM3神经节苷脂在无胸腺裸鼠排斥的三个细胞系中是主要成分之一。相反,在三个致瘤细胞系中,GM3不存在或仅微量存在。

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