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[女性内分泌干扰物与生殖障碍]

[Endocrine disrupter and reproductive disorders in women].

作者信息

Sone H

机构信息

National Institute for Environmental Studies, Regional Environment Division.

出版信息

Nihon Rinsho. 2000 Dec;58(12):2521-6.

Abstract

Endocrine disrupters, which are exogenous substances with estrogenic or other hormonally active properties, may adversely affect the reproductive health of both women and men. The resulting disorders can include cancer development in hormonally sensitive tissues, structural alteration of reproductive organs, and delay or acceleration of the estrus cycle. However, the available laboratory and epidemiological data do not provide consistent or convincing evidence that industrial chemicals suspected of modulating estrogenic pathways are responsible for adverse health effects in women. The present review covers the recent literature and assesses the risk of endocrine disrupters to the reproductive health of women.

摘要

内分泌干扰物是具有雌激素或其他激素活性特性的外源性物质,可能对女性和男性的生殖健康产生不利影响。由此产生的疾病可能包括激素敏感组织中的癌症发展、生殖器官的结构改变以及发情周期的延迟或加速。然而,现有的实验室和流行病学数据并未提供一致或令人信服的证据,证明怀疑调节雌激素途径的工业化学品会对女性健康产生不良影响。本综述涵盖了近期文献,并评估了内分泌干扰物对女性生殖健康的风险。

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