Sandén B, Olerud C, Johansson C, Larsson S
Department of Orthopaedic Surgery, Uppsala University Hospital, Sweden.
Eur Spine J. 2000 Dec;9(6):534-7. doi: 10.1007/s005860000180.
Loosening of the screws is a problem in instrumentation with pedicle screws. Coating with hydroxyapatite improves the holding characteristics for metal implants, but the possible effects on the anchorage of pedicle screws have not been described. In this study, seven patients were operated on with spinal instrumentation using four stainless steel pedicle screws. Hydroxyapatite-coated screws were used in either the upper or the lower of the instrumented levels. The insertion torque was measured. In four cases the screws were removed after 10-22 months and the extraction torque was measured. The mean insertion torque was found to be significantly greater in the hydroxyapatite-coated screws (107 Ncm) than in the standard screws (76 Ncm). In three cases, the extraction torque for the hydroxyapatite-coated screws exceeded the range for the torque wrench (600 Ncm), while the conventional screws were loose (< 5 Ncm). In one case, the extraction torque was 475 and 550 Ncm for the coated screws, and 5 and 25 Ncm for the conventional screws. The difference in extraction torque was significant. Hydroxyapatite coating was shown to have improved the purchase of pedicle screws very effectively. By using fully coated screws, as in the present study, extraction was extremely difficult compared to extraction of conventional stainless steel screws, which were regularly loose. By reducing the area of the screws that is coated, it may be possible to achieve an enhanced purchase while extraction will be easier when compared to fully coated screws.
椎弓根螺钉内固定术中螺钉松动是一个问题。羟基磷灰石涂层可改善金属植入物的固定特性,但对椎弓根螺钉锚固的可能影响尚未见报道。在本研究中,7例患者接受了使用4枚不锈钢椎弓根螺钉的脊柱内固定手术。羟基磷灰石涂层螺钉用于内固定节段的上半部分或下半部分。测量了插入扭矩。4例患者在10 - 22个月后取出螺钉并测量了拔出扭矩。结果发现,羟基磷灰石涂层螺钉的平均插入扭矩(107 Ncm)显著高于标准螺钉(76 Ncm)。3例中,羟基磷灰石涂层螺钉的拔出扭矩超过了扭矩扳手的范围(600 Ncm),而传统螺钉松动(< 5 Ncm)。1例中,涂层螺钉的拔出扭矩为475和550 Ncm,传统螺钉为5和2 Ncm。拔出扭矩差异显著。结果表明,羟基磷灰石涂层非常有效地改善了椎弓根螺钉的固定。如本研究中使用全涂层螺钉,与经常松动的传统不锈钢螺钉相比,取出极为困难。通过减少螺钉的涂层面积,可能在实现增强固定的同时,与全涂层螺钉相比,取出会更容易。