Ho G Y, Windsor H M
NHMRC Helicobacter pylori Research Laboratory, Department of Microbiology, University of Western Australia, Nedlands, Perth, Western Australia.
Gastroenterol Clin North Am. 2000 Dec;29(4):903-15. doi: 10.1016/s0889-8553(05)70158-8.
Although PCR has improved considerably the sensitivity of the diagnosis of H. pylori infection, many studies have not shown conclusively the full potential of PCR in clinical diagnosis. In daily clinical practice, PCR does not have to be performed to establish H. pylori infection. PCR is still classified primarily as a research technique in the Helicobacter field. PCR or similar technology will expand in the future when automation and commercialized kits are available to most laboratories. The development of a noninvasive PCR test may prove useful because it may lead ultimately to the determination of the source and route of transmission of this important pathogen.
尽管聚合酶链反应（PCR）已显著提高了幽门螺杆菌感染诊断的敏感性，但许多研究尚未确凿地证明PCR在临床诊断中的全部潜力。在日常临床实践中，并不一定需要通过PCR来确诊幽门螺杆菌感染。在幽门螺杆菌领域，PCR仍主要归类为一种研究技术。当自动化设备和商业化试剂盒可供大多数实验室使用时，PCR或类似技术在未来将会得到更广泛应用。开发一种非侵入性的PCR检测方法可能会被证明是有用的，因为这最终可能有助于确定这种重要病原体的来源和传播途径。
