喉切除术后咽皮肤瘘的发生率及病因

The incidence and etiology of postlaryngectomy pharyngocutaneous fistulae.

作者信息

Virtaniemi J A, Kumpulainen E J, Hirvikoski P P, Johansson R T, Kosma V M

机构信息

Department of Otorhinolaryngology, University of Kuopio and Kuopio University Hospital, Finland.

出版信息

Head Neck. 2001 Jan;23(1):29-33.

DOI:
Abstract

BACKGROUND

The pharyngocutaneous fistula is troublesome complication after total laryngectomy. Despite a large number of studies, there is still disagreement on factors predisposing to this complication.

METHODS

A retrospective analysis of pharyngocutaneous fistulas in 133 patients in whom total laryngectomy was performed.

RESULTS

Fistulas were found in 15% of the patients. Spontaneous closure was noted in 80%. Simultaneous laryngectomy and partial pharyngectomy or neck dissection increased the risk of fistula formation. Preoperative irradiation, short interval between radiotherapy and operation, and cobalt/roentgen radiation instead of photons predispose to this complication. The fistulas appeared earlier, and the sizes of fistulas were significantly larger in patients with previous irradiation than those in patients with no preoperative irradiation.

CONCLUSIONS

Postoperative pharyngocutaneous fistulas significantly increase patients' morbidity and hospital stay. Good surgical technique and postoperative treatment should be paid attention to patients with an increased risk of pharyngocutaneous fistula formation.

摘要

背景

咽皮肤瘘是全喉切除术后令人困扰的并发症。尽管有大量研究,但对于该并发症的易感因素仍存在分歧。

方法

对133例行全喉切除术患者的咽皮肤瘘进行回顾性分析。

结果

15%的患者出现瘘管。80%的瘘管实现了自发闭合。同期行喉切除术和部分咽切除术或颈部清扫术会增加瘘管形成的风险。术前放疗、放疗与手术间隔时间短以及使用钴/伦琴射线而非光子放疗易引发该并发症。与未接受术前放疗的患者相比,曾接受放疗的患者瘘管出现得更早,且瘘管尺寸明显更大。

结论

术后咽皮肤瘘显著增加患者的发病率和住院时间。对于咽皮肤瘘形成风险增加的患者,应注重良好的手术技术和术后治疗。

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