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[全喉切除术并发症与既往放疗的关系]

[Complications of total laryngectomy in relation to the previous radiotherapy].

作者信息

Venegas M P, León X, Quer M, Matiño E, Montoro V, Burgués J

机构信息

Servicio de ORL, Hospital de la Santa Creu i Sant Pau, Barcelona.

出版信息

Acta Otorrinolaringol Esp. 1997 Nov-Dec;48(8):639-46.

PMID:9580286
Abstract

Different factors, particularly prior radiotherapy, are associated with the occurrence of postoperative complications after total laryngectomy. We compared the postoperative complications of 50 patients who underwent total laryngectomy without prior radiotherapy and those of 50 patients who underwent total laryngectomy for tumor recurrence or persistence after radiotherapy. Twenty-four percent of the patients without previous irradiation suffered cervical complications compared with 26% of the patients with previous irradiation. The most frequent cervical complication was pharyngo-cutaneous fistula, which occurred in 12% of the non-irradiated patients and in 18% of the irradiated patients. There were no significant differences in the frequency of complications or in the occurrence of fistulas in relation to prior radiotherapy. In the group of irradiated patients, the proportion of major fistulas was greater. The occurrence of cervical complications, particularly pharyngo-cutaneous fistulas, significantly prolonged the hospital stay.

摘要

不同因素,尤其是既往放疗史,与全喉切除术后并发症的发生有关。我们比较了50例未接受过放疗而行全喉切除术患者与50例因放疗后肿瘤复发或持续存在而行全喉切除术患者的术后并发症情况。未接受过放疗的患者中有24%发生颈部并发症,而接受过放疗的患者中这一比例为26%。最常见的颈部并发症是咽皮肤瘘,在未接受放疗的患者中发生率为12%,在接受过放疗的患者中为18%。在并发症发生率或瘘的发生方面,与既往放疗史并无显著差异。在接受过放疗的患者组中,大瘘的比例更高。颈部并发症的发生,尤其是咽皮肤瘘,显著延长了住院时间。

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