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[与高血压和脑血管动脉粥样硬化相关的脑循环障碍中的自身免疫因素]

[Autoimmune factors in cerebral circulatory disorders associated with hypertension and atherosclerosis of the cerebral vessels].

作者信息

Savenko S N, Polienko E M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(1):3-7.

PMID:1119237
Abstract

In 160 patients with disorders of brain circulation in cerebral atherosclerosis, 68 normals and 38 patients with different neurological diseases (a control group), a special study was undertaken to study the antibrain antibodies with the aid of a complement fixation test (CFT), and a test of complement utilization (CUT). Positive results in the CFT and CUT were seen in patients with ischemic strokes and transient disorders of brain circulation. The formation of antibodies to brain tissues depends upon their type, duration of the disease and is more characteristic of the rehabilitation period. In studying autoimmune processes in patients with disordered brain circulation previous diseases should be taken into consideration (brain trauma, epilepsy, strokes). The existence of antibrain antibodies correlates with the intensity of the process.

摘要

在160例脑动脉粥样硬化性脑循环障碍患者、68例正常人及38例患有不同神经系统疾病的患者(对照组)中,借助补体结合试验(CFT)和补体利用试验(CUT)进行了一项关于抗脑抗体的专项研究。在缺血性中风和短暂性脑循环障碍患者中,CFT和CUT检测结果呈阳性。针对脑组织的抗体形成取决于疾病类型、病程,且在康复期更具特征性。在研究脑循环障碍患者的自身免疫过程时,应考虑既往疾病(脑外伤、癫痫、中风)。抗脑抗体的存在与病情严重程度相关。

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