Maeno Y, Sando Y, Ubukata M, Maeno T, Tajima S, Hosono T, Sato M, Tsukagoshi M, Suga T, Kurabayashi M, Nagai R
Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan.
Respirology. 2000 Dec;5(4):393-5.
Nocardiosis is a subacute or chronic suppurative infection caused by Nocardia species. Although it is more common in immunocompromised hosts, idiopathic pulmonary fibrosis (IPF) has not been recognized as a predisposing factor for nocardial infection. We report a case of IPF, in which pulmonary nocardiosis developed during treatment with prednisolone and cyclophosphamide. The risk of pulmonary nocardiosis may be increased in cases of IPF on immunosuppressive therapy. Since IPF often accompanies lung carcinoma, it is important to correctly differentiate nocardiosis from carcinoma.
诺卡菌病是由诺卡菌属引起的亚急性或慢性化脓性感染。虽然在免疫功能低下的宿主中更为常见，但特发性肺纤维化（IPF）尚未被认为是诺卡菌感染的易感因素。我们报告一例IPF患者，其在接受泼尼松龙和环磷酰胺治疗期间发生了肺诺卡菌病。接受免疫抑制治疗的IPF患者发生肺诺卡菌病的风险可能会增加。由于IPF常伴有肺癌，因此正确区分诺卡菌病和癌症很重要。
