新型儿茶酚胺释放抑制肽癌抑素（嗜铬粒蛋白A344 - 364）。特性与功能。 - Suppr

The novel catecholamine release-inhibitory peptide catestatin (chromogranin A344-364). Properties and function.

作者信息

Mahata S K, Mahata M, Livsey Taylor C V, Taupenot L, Parmer R J, O'Connor D T

机构信息

Department of Medicine and Center for Molecular Genetics, University of California, and Veterans Affairs, San Diego Healthcare System, San Diego, California 92161-9111, USA.

出版信息

Adv Exp Med Biol. 2000;482:263-77. doi: 10.1007/0-306-46837-9_21.

DOI:10.1007/0-306-46837-9_21

PMID:11192587

Abstract

摘要

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The novel catecholamine release-inhibitory peptide catestatin (chromogranin A344-364). Properties and function.新型儿茶酚胺释放抑制肽癌抑素（嗜铬粒蛋白A344 - 364）。特性与功能。

Adv Exp Med Biol. 2000;482:263-77. doi: 10.1007/0-306-46837-9_21.

Primary structure and function of the catecholamine release inhibitory peptide catestatin (chromogranin A(344-364)): identification of amino acid residues crucial for activity.儿茶酚胺释放抑制肽癌抑素（嗜铬粒蛋白A(344 - 364)）的一级结构与功能：对活性至关重要的氨基酸残基的鉴定

Mol Endocrinol. 2000 Oct;14(10):1525-35. doi: 10.1210/mend.14.10.0531.

Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.儿茶酚胺释放的新型自分泌反馈控制。一种离散的嗜铬粒蛋白A片段是一种非竞争性烟碱胆碱能拮抗剂。

J Clin Invest. 1997 Sep 15;100(6):1623-33. doi: 10.1172/JCI119686.

The catecholamine release-inhibitory "catestatin" fragment of chromogranin a: naturally occurring human variants with different potencies for multiple chromaffin cell nicotinic cholinergic responses.嗜铬粒蛋白A的儿茶酚胺释放抑制性“抑嗜素”片段：具有不同效力的天然存在的人类变体对多种嗜铬细胞烟碱能胆碱能反应的影响

Mol Pharmacol. 2004 Nov;66(5):1180-91. doi: 10.1124/mol.104.002139. Epub 2004 Aug 23.

The chromogranin A fragment catestatin: specificity, potency and mechanism to inhibit exocytotic secretion of multiple catecholamine storage vesicle co-transmitters.嗜铬粒蛋白A片段癌抑素：抑制多种儿茶酚胺储存囊泡共递质胞吐分泌的特异性、效力及机制

J Hypertens. 2006 May;24(5):895-904. doi: 10.1097/01.hjh.0000222760.99852.e0.

Conformational preferences and activities of peptides from the catecholamine release-inhibitory (catestatin) region of chromogranin A.嗜铬粒蛋白A的儿茶酚胺释放抑制（抑癌素）区域肽段的构象偏好性与活性

Regul Pept. 2004 Apr 15;118(1-2):75-87. doi: 10.1016/j.regpep.2003.10.035.

Interaction of the catecholamine release-inhibitory peptide catestatin (human chromogranin A(352-372)) with the chromaffin cell surface and Torpedo electroplax: implications for nicotinic cholinergic antagonism.儿茶酚胺释放抑制肽癌抑素（人嗜铬粒蛋白A(352 - 372)）与嗜铬细胞表面及电鳐电板的相互作用：对烟碱型胆碱能拮抗作用的影响

Regul Pept. 2000 Nov 24;95(1-3):9-17. doi: 10.1016/s0167-0115(00)00135-x.

Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance.儿茶酚胺释放的脱敏作用。新型儿茶酚胺释放抑制肽癌抑素（嗜铬粒蛋白A344 - 364）作用于受体以防止烟碱型胆碱能耐受。

J Biol Chem. 1999 Jan 29;274(5):2920-8. doi: 10.1074/jbc.274.5.2920.

A novel, catecholamine release-inhibitory peptide from chromogranin A: autocrine control of nicotinic cholinergic-stimulated exocytosis.一种源自嗜铬粒蛋白A的新型儿茶酚胺释放抑制肽：烟碱型胆碱能刺激的胞吐作用的自分泌控制

Adv Pharmacol. 1998;42:260-4. doi: 10.1016/s1054-3589(08)60743-7.

Catecholamine secretory vesicle stimulus-transcription coupling in vivo. Demonstration by a novel transgenic promoter/photoprotein reporter and inhibition of secretion and transcription by the chromogranin A fragment catestatin.体内儿茶酚胺分泌囊泡的刺激-转录偶联。通过新型转基因启动子/光蛋白报告基因进行的证明以及嗜铬粒蛋白A片段卡替他汀对分泌和转录的抑制作用。

J Biol Chem. 2003 Aug 22;278(34):32058-67. doi: 10.1074/jbc.M305545200. Epub 2003 Jun 10.

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Sci Rep. 2018 Jun 18;8(1):9235. doi: 10.1038/s41598-018-27417-x.

Cardiac electrical activity in a genomically "humanized" chromogranin a monogenic mouse model with hyperadrenergic hypertension.在具有高肾上腺素能性高血压的基因组“人源化”嗜铬粒蛋白a单基因小鼠模型中的心脏电活动。

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PACAP-cytokine interactions govern adrenal neuropeptide biosynthesis after systemic administration of LPS.PACAP-细胞因子相互作用控制全身给予 LPS 后肾上腺神经肽的生物合成。

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An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension.嗜铬粒蛋白II的一个祖先变体受PHOX2转录因子调控并与高血压相关。

Hum Mol Genet. 2007 Jul 15;16(14):1752-64. doi: 10.1093/hmg/ddm123. Epub 2007 Jun 21.

Tetrapeptides on N- and C-terminal regions of mastoparan inhibit catecholamine release from chromaffin cells by blocking nicotinic acetylcholine receptor.mastoparan N端和C端区域的四肽通过阻断烟碱型乙酰胆碱受体抑制嗜铬细胞释放儿茶酚胺。

Cell Mol Neurobiol. 2004 Feb;24(1):37-50. doi: 10.1023/b:cemn.0000012723.52742.84.

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The novel catecholamine release-inhibitory peptide catestatin (chromogranin A344-364). Properties and function.

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