Singh G, Katyal S L
Department of Veterans Affairs and Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA.
Ann N Y Acad Sci. 2000;923:43-58. doi: 10.1111/j.1749-6632.2000.tb05518.x.
Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10-kDa protein/uteroglobin. This protein consists of a homodimer of 70-77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.