Ziebold C, von Kries R, Siedler A, Schmitt H J
Department of Pediatrics, Johannes-Gutenberg University, Mainz, Germany.
Acta Paediatr Suppl. 2000 Dec;89(435):17-21. doi: 10.1111/j.1651-2227.2000.tb00777.x.
Recently published and as yet unpublished data allow a reasonable estimate of the annual burden of pneumococcal disease in Germany. At least 277,000 episodes of otitis media and at least 2,000 episodes of sinusitis occur in children under the age of 5 y. Pneumococcal meningitis was found in 200 children under the age of 16 y; the estimate for all age groups ranges from 450 to 1100 cases. Of approximately 150,000 cases of ambulatory pneumococcal pneumonia, at least 63,000-105,000 patients are hospitalized each year.
Further studies of pneumococcal epidemiology in Germany are needed, and continued surveillance will be necessary for a better understanding of the overall burden of pneumococcal disease in children as well as adults.
最近公布的以及尚未公布的数据使得对德国肺炎球菌疾病的年度负担进行合理估计成为可能。5岁以下儿童中至少发生27.7万次中耳炎发作以及至少2000次鼻窦炎发作。在16岁以下儿童中发现了200例肺炎球菌性脑膜炎;所有年龄组的估计病例数在450至1100例之间。在约15万例门诊肺炎球菌肺炎病例中,每年至少有6.3万至10.5万名患者住院。
需要在德国进一步开展肺炎球菌流行病学研究,持续监测对于更好地了解儿童及成人肺炎球菌疾病的总体负担将是必要的。