Department of Paediatric Infectious Diseases and Immunology,University Children's Hospital,Würzburg,Germany.
Department of Clinical Sciences, Pediatrics,Umeå University,Umeå,Sweden.
Epidemiol Infect. 2014 Aug;142(8):1778-88. doi: 10.1017/S0950268813002744. Epub 2013 Dec 13.
We conducted an epidemiological, observational cohort study to determine the incidence and complications of acute otitis media (AOM) in children aged <6 years. Data on physician-diagnosed AOM were collected from retrospective review of medical charts for the year preceding enrolment and then prospectively in the year following enrolment. The study included 5776 children in Germany, Italy, Spain, Sweden, and the UK. AOM incidence was 256/1000 person-years [95% confidence interval (CI) 243-270] in the prospective study period. Incidence was lowest in Italy (195, 95% CI 171-222) and highest in Spain (328, 95% CI 296-363). Complications were documented in <1% of episodes. Spontaneous tympanic membrane perforation was documented in 7% of episodes. Both retrospective and prospective study results were similar and show the high incidence during childhood in these five European countries. Differences by country may reflect true differences and differences in social structure and diagnostic procedures.
我们开展了一项流行病学、观察性队列研究，以确定 6 岁以下儿童急性中耳炎（AOM）的发病率和并发症。在入组前一年的回顾性病历审查和入组后一年的前瞻性研究中收集了医生诊断为 AOM 的数据。该研究纳入了德国、意大利、西班牙、瑞典和英国的 5776 名儿童。前瞻性研究期间，AOM 的发病率为 256/1000 人年（95%置信区间[CI]为 243-270）。发病率最低的是意大利（195，95%CI 为 171-222），最高的是西班牙（328，95%CI 为 296-363）。并发症在不到 1%的病例中得到记录。7%的病例中记录了自发性鼓膜穿孔。回顾性和前瞻性研究结果相似，均表明这五个欧洲国家在儿童时期的发病率较高。国家间的差异可能反映了真实差异以及社会结构和诊断程序的差异。
Zotero 插件