呼气末正压（PEEP）在递增运动期间对通气反应有轻微影响。

Positive end expiratory pressure (PEEP) slightly modifies ventilatory response during incremental exercise.

作者信息

Savourey G, Besnard Y, Launay J C, Guinet A, Hanniquet A M, Sendowski I, Caterini R, Bittel J

机构信息

Unité de Thermophysiologie, Centre de Recherches du Service de Santé des Armées, La Tronche, France.

出版信息

Aviat Space Environ Med. 2001 Jan;72(1):21-4.

PMID:11194989

Abstract

To clarify the ventilatory effects of a 5-cm H2O positive end expiratory pressure (PEEP) in healthy men during incremental exercise in normoxic conditions, 22 subjects were subjected to a constant workload (0 W, 50 W, 100 W, 150 W and 200 W) on a cycle ergometer for periods of 8 min each, both with and without 5-cm H2O PEEP. Results show that PEEP increases inspiratory (TI) and expiratory (TE) duration and tidal volume (VT) and decreases breathing frequency (fB) at rest (p < 0.05). During exercise, TI is higher at 50 W and 100 W (p < 0.05), but not at 150 and 200 W. TE only increases at 50 W (p < 0.05). An increased VT (p < 0.05 at 50, 100 and 150 W) and a decreased fB (p < 0.05 throughout the experiment) were observed. However, mean inspiratory flow (VT/T1) and duty cycle (TI/TT) were unaffected by PEEP. In conclusion, this study shows that a 5-cm H2O PEEP slightly modifies the ventilatory parameters in healthy subjects during incremental exercise in normoxic conditions.

摘要

为阐明在常氧条件下递增运动期间5厘米水柱呼气末正压（PEEP）对健康男性通气的影响，22名受试者在功率自行车上进行恒定负荷（0瓦、50瓦、100瓦、150瓦和200瓦）运动，每次运动8分钟，分别在有和无5厘米水柱PEEP的情况下进行。结果显示，PEEP增加静息时的吸气时间（TI）、呼气时间（TE）和潮气量（VT），并降低呼吸频率（fB）（p<0.05）。运动期间，50瓦和100瓦时TI较高（p<0.05），但150瓦和200瓦时并非如此。TE仅在50瓦时增加（p<0.05）。观察到VT增加（50瓦、100瓦和150瓦时p<0.05）和fB降低（整个实验过程中p<0.05）。然而，平均吸气流量（VT/T1）和占空比（TI/TT）不受PEEP影响。总之，本研究表明，在常氧条件下递增运动期间，5厘米水柱PEEP会轻微改变健康受试者的通气参数。